A synthesized peptide derived from human TSLP, corresponding to a region within the internal amino acids.
This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants.
A synthesized peptide derived from human TSN, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human TSNAX.
A synthesized peptide derived from human TSP50, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human TSPAN10.
A synthesized peptide derived from human TSPAN12.
A synthesized peptide derived from human TSPAN13.
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.
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