TUBG2 (Tubulin Gamma 2) is a Protein Coding gene. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and Sertoli-Sertoli Cell Junction Dynamics. Gene Ontology (GO) annotations related to this gene include GTP binding and structural molecule activity. An important paralog of this gene is TUBG1.
A synthesized peptide derived from human TUBGCP2, corresponding to a region within the internal amino acids.
Gamma-tubulin complex component 2is aproteinthat in humans is encoded by theTUBGCP2gene. It is part of the gamma tubulin complex, which required formicrotubule nucleationat thecentrosome. Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome. Gamma-tubulin complex is composed of gamma-tubulin, TUBGCP2, TUBGCP3, TUBGCP4, TUBGCP5 and TUBGCP6.
A synthesized peptide derived from human TUBGCP3, corresponding to a region within N-terminal amino acids.
A synthesized peptide derived from human TUBGCP4, corresponding to a region within the internal amino acids.
This gene encodes a component of the gamma-tubulin ring complex, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants.TUBGCP4 (Tubulin Gamma Complex Associated Protein 4) is a Protein Coding gene. Diseases associated with TUBGCP4 include Microcephaly And Chorioretinopathy, Autosomal Recessive, 3 and Autosomal Recessive Chorioretinopathy-Microcephaly Syndrome. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and Cell Cycle, Mitotic. GO annotations related to this gene include structural constituent of cytoskeleton. An important paralog of this gene is TUBGCP6.
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