A synthesized peptide derived from human USP7, corresponding to a region within the internal amino acids.
The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM24, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder.
A synthesized peptide derived from human USP9X, corresponding to a region within N-terminal amino acids.
This gene is a member of the peptidase C19 family and encodes a protein that is similar to ubiquitin-specific proteases. Though this gene is located on the X chromosome, it escapes X-inactivation. Mutations in this gene have been associated with Turner syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
A synthesized peptide derived from human UTP11.
A synthesized peptide derived from human UTP20.
Essential for gene silencing: has a role in the structure of silenced chromatin. Plays a role in the developing brain (By similarity).
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