TheZBTB6protein contains a conserved N-terminal domain known as the POZ domain that inhibits DNA binding. Sequence analysis predicted that the 424-amino acid protein contains 4 C-terminal zinc finger motifs and an N-terminal domain of 120 amino acids found in many different zinc finger proteins and a group of non-zinc finger poxvirus proteins.
LRF, formerly identified as Pokemon, is a poxvirus zinc finger (POZ) domain-containing transcription factor that influences cell differentiation. LRF (for leukemia/lymphoma related factor) is also known as zinc finger and BTB domain containing 7A, ZBTB7, TIP21, FBI1 and FBI-1. POZ-domain transcription factors contain a POZ or BTB type protein-protein interaction domain at their N-terminus and Kruppel-type zinc fingers at their C-terminus. LRF is inducible during both murine and human preadipocyte differentiation and may contrib-ute to adipogenesis through influencing the switch from cellular proliferation to terminal differentiation.
ZBTB7B Antibody detects endogenous levels of ZBTB7B.
ZBTB7C Antibody detects endogenous levels of ZBTB7C.
ZBTB7C Mouse Monoclonal Antibody detects endogenous levels of ZBTB7C.
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