This gene is a member of the zyxin family and encodes a protein with three LIM zinc-binding domains. This protein localizes to focal adhesion sites and along actin stress fibers. Recruitment of this protein to the plasma membrane occurs in a lysophosphatidic acid (LPA)-dependent manner and it regulates LPA-induced cell migration. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
A synthesized peptide derived from human Tristetraprolin, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human Trk A.
A synthesized peptide derived from human TrkA, corresponding to a region within the internal amino acids.
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