A synthesized peptide derived from human TrkA, corresponding to a region within C-terminal amino acids.
A synthesized peptide derived from human TrkA, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human TrkA around the site of Tyr680.
A synthetic peptide from human TrkA
A synthesized peptide derived from human TrkA /TrkB, corresponding to a region within C-terminal amino acids.
A synthetic peptide from human Trk B
A synthesized peptide derived from human TrkC, corresponding to a region within C-terminal amino acids.
A synthesized peptide derived from human TrkC.
This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene.
A synthesized peptide derived from human TRMT10C.
The protein encoded by this gene is a transcriptional regulator and oncoprotein that may be involved in hematopoiesis, apoptosis, development, and cell differentiation and proliferation. The encoded protein can interact with CTBP1, SMAD3, CREBBP, KAT2B, MAPK8, and MAPK9. This gene can undergo translocation with the AML1 gene, resulting in overexpression of this gene and the onset of leukemia. Several transcript variants encoding a few different isoforms have been found for this gene.
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