A synthetic peptide from human ULK1
A synthesized peptide derived from human ULK2, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human ULK3, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human ULK4, corresponding to a region within the internal amino acids.
ULK4 (unc-51-like kinase 4) is a 1,275 amino acid protein that contains one protein kinase domain and one HEAT repeat and belongs to the Ser/Thr protein kinase family. Although containing what is thought to be a catalytically inactive domain, ULK4 may play a role in the ATP-dependent phosphorylation of target proteins. The gene encoding ULK4 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci.
A synthesized peptide derived from human UMOD, corresponding to a region within C-terminal amino acids.
The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN). Alternative splicing of this gene results in multiple transcript variants.
A synthesized peptide derived from human UMP/CMP kinase, corresponding to a region within N-terminal amino acids.
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