C6ORF55 encodes a protein involved in trafficking of the multivesicular body, an endosomal compartment involved in sorting membrane proteins for degradation in lysosomes (Ward et al., 2005 [PubMed 15644320]).
A synthesized peptide derived from human VTCN1, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human VTI1A, corresponding to a region within the internal amino acids.
The protein encoded by this gene is a member of the family of soluble N-ethylmaleimide-sensitive fusion protein-attachment protein receptors (SNAREs) that function in intracellular trafficking. This family member is involved in vesicular transport between endosomes and the trans-Golgi network. It is a vesicle-associated SNARE (v-SNARE) that interacts with target membrane SNAREs (t-SNAREs). Polymorphisms in this gene have been associated with binocular function, and also with susceptibility to colorectal and lung cancers. A recurrent rearrangement has been found between this gene and the transcription factor 7-like 2 (TCF7L2) gene in colorectal cancers. Alternative splicing results in multiple transcript variants.
A synthesized peptide derived from human VTI1B, corresponding to a region within the internal amino acids.
VTI1B (Vesicle Transport Through Interaction With T-SNAREs 1B) is a Protein Coding gene. Diseases associated with VTI1B includeHypomyelinating Leukodystrophy. Among its related pathways arewtCFTR and deltaF508 traffic / Late endosome and Lysosome (norm and CF)andResponse to elevated platelet cytosolic Ca2+. Gene Ontology (GO) annotations related to this gene includeSNARE bindingandchloride channel inhibitor activity. An important paralog of this gene isVTI1A.
Inserisci la tua e-mail e seleziona le aree di interesse per ricevere le ultime novità, approfondimenti e promozioni.
Seleziona uno o più ambiti di interesse per ricevere comunicazioni più utili e mirate.
2025 TEMA Ricerca - All Rights Reserved.
