VTI1B (Vesicle Transport Through Interaction With T-SNAREs 1B) is a Protein Coding gene. Diseases associated with VTI1B includeHypomyelinating Leukodystrophy. Among its related pathways arewtCFTR and deltaF508 traffic / Late endosome and Lysosome (norm and CF)andResponse to elevated platelet cytosolic Ca2+. Gene Ontology (GO) annotations related to this gene includeSNARE bindingandchloride channel inhibitor activity. An important paralog of this gene isVTI1A.
A synthesized peptide derived from human VTN, corresponding to a region within the internal amino acids.
The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond.
Vitronectin is a glycoprotein present in blood and in the extracellular matrix . Vitronectin is a multifunctional glycoprotein that mediates cell-to-substrate adhesion,inhibits the cytolytic action of the terminal complement cascade in vitro and binds to several serine protease inhibitors of the serpin family .
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