This protein mediates pre-mRNA alternative splicing regulation. It binds to splice sites in pre-mRNA and regulates splice site selection and contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors. It can regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro).
A synthesized peptide derived from human YBX3.
A synthesized peptide derived from human YEATS2, corresponding to a region within the internal amino acids.
The protein encoded by this gene is a scaffolding subunit of the ATAC complex, which is a complex with acetyltransferase activity on histones H3 and H4. Alternative splicing results in multiple transcript variants encoding different isoforms.YEATS2 (YEATS Domain Containing 2) is a Protein Coding gene. Among its related pathways are Chromatin organization. GO annotations related to this gene include TBP-class protein binding. An important paralog of this gene is YEATS4.
A synthesized peptide derived from human YME1L1, corresponding to a region within C-terminal amino acids.
A synthesized peptide derived from human YOD1, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human YPEL3, corresponding to a region within N-terminal amino acids.
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