ZNHIT3 (zinc finger, HIT-type containing 3), also known as TRIP3 (thyroid receptor-interacting protein 3) or HNF-4a coactivator, is a 155 amino acid protein that contains one HIT-type zinc finger and regulates PPAR-mediated adipocyte differentiation. ZNHIT3 also coactivates HNF-4, and as a thyroid receptor interacting protein, ZNHIT3 interacts with the ligand binding domain of the thyroid receptor. The gene encoding ZNHIT3 maps to human chromosome 17, which comprises over 2.5% of the human genome and encodes over 1,200 genes. Two key tumor suppressor genes are associated with chromosome 17, namely, p53 and BRCA1. Malfunction or loss of p53 expression is associated with malignant cell growth and Li-Fraumeni syndrome. Like p53, BRCA1 is directly involved in DNA repair, though specifically it is recognized as a genetic determinant of early onset breast cancer and predisposition to cancers of the ovary, colon, prostate gland and fallopian tubes.
A synthesized peptide derived from human ZNRD1, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human ZNRF1, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human ZNRF2.
A synthesized peptide derived from Human ZNRF3.
A synthesized peptide derived from human ZnT3, corresponding to a region within C-terminal amino acids.
A synthesized peptide derived from human ZnT6, corresponding to a region within the internal amino acids.
A synthesized peptide derived from human ZnT7, corresponding to a region within N-terminal amino acids.
A synthesized peptide derived from human ZO 1, corresponding to a region within the internal amino acids.
A synthetic peptide from human ZO 1
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